In the USA and Mexico, one in every 650 births has a cleft deformity.
While worldwide numbers differ according to regional ethnicity, several
environmental factors such as exposure of the mother to harmful substances
and mal-nutrition have been implicated to increase this number.
While the reasons for infant clefting are multifactoral, clearly genetic
heredity plays the most important role. Usually the cleft lip is closed at
age 10 weeks and the palate at approximately one year. Other staged
corrections include ear tubes, nasal correction, bone grafts, and
maxillofacial dental prosthetics.
If done at the appropriate times throughout development, favorable outcomes
are possible with esthetics and functional speech, hearing, and the ability
to eat. In less fortunate regions of the world, socio-economic conditions
can lead to a delay of these treatments for the child, if corrected at all.
This produces children developing with severe deformities more difficult to
correct later in life and social out casting of the child.